Inhibitors of Serine Proteinase – Application in Agriculture and Medicine

Inhibitors are important elements of regulation of enzyme activity. They can be named ubiquitous components in living organisms (Fan & Wu, 2005). There is a number of inhibitors, such as protein and nonprotein. Among all inhibitors, the most significant are inhibitors of hydrolytic enzymes. Hydrolases are enzymes that catalyze the hydrolysis of chemical bonds. For example, proteolytic enzymes (peptidases or proteinases) hydrolyse the peptide bond, glycosidic glycosidases, esterases hydrolytically cleave the ester bond (The Enzyme List, 2010). The inhibitors of hydrolases was found in bacteria, plants, fungi and animals (Rawlings et al., 2004).